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A Journal on Diseases of the Respiratory System

Official Journal of the Italian Society of Thoracic Endoscopy
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Minerva Pneumologica 2006 September;45(3):161-8

language: Italian

Pharmacological prophylaxis for acute exacerbation of chronic obstructive pulmonary disease

Marzo B., Grella E.

Sezione di Pneumologia Dipartimento di Scienze Cardiotoraciche e Respiratorie A. O. Monaldi, Napoli


Chronic obstructive pulmonary disease and its acute exacerbations have a considerable impact on public health care. Lower respiratory infections accounted for 4% of all visits in Italy during the 2-year period from 2000 to 2001. Of the nearly 16.5 million cases, 38% represented referrals for chronic bronchitis and its acute exacerbations. These figures underline the importance of pharmacological control during periods of quiescence for reducing disease progression, mortality, and symptoms, as well as prevention of exacerbation. Contingent to this strategy is prophylactic therapy to increase immune response, reduce duration and severity of episodes, simplify patient management and reduce costs, and improve the patient’s quality of life.

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