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Minerva Pneumologica 2004 September;43(3):131-42

Copyright © 2004 EDIZIONI MINERVA MEDICA

language: Italian

Prognostic factors in advanced stage non-small cell lung cancer

Buccheri G., Ferrigno D., Barisione E., Noceti P.


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Prognostic factors continue to play a critical role in explaining the survival of lung cancer patients and prove highly important in many clinical tasks including individual counselling, the choice of treatment options, the stratification of patients by comparable risk groups and understanding the biological nature of the disease. Traditionally, the anatomic extent of the disease, the patient's performance status, and just a few other anthropometric variables are considered indispensable for a reliable prognostic assessment. Particularly in small cell lung cancer, but also in the advanced stages of non-small cell cancer, the use of simple biochemical tests is considered a valuable supplementary option. For years, for example, serum tumour markers have been used to monitor the clinical course of patients with lung cancer and their prognostic capacity is at this stage absolutely certain. More recently, some prognostic determinants of a biological nature have attracted the attention of researchers by offering new fields of research and clinical application.

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