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A Journal on Diseases of the Respiratory System
Official Journal of the Italian Society of Thoracic Endoscopy
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Minerva Pneumologica 2003 March;42(1):31-4
Solitary meningeal carcinomatosis from lung cancer with 8-year disease-free interval. Report of a case
Kamiyoshihara M., Sakata K., Otani Y., Kawashima O., Takahashi T., Morishita Y.
We report an ultimately rare case of solitary leptomeningeal carcinomatosis (LMC) from lung cancer with 8-year disease-free interval. A 62-year-old man had undergone a right upper lobectomy with mediastinal lymph node dissection for primary pulmonary adenocarcinoma. Eight years later, the patient experienced an epileptic seizure and an aprophoria. A biopsy of the brain was performed and yielded a diagnosis of metastatic LMC from lung cancer. However, there was no metastatic or recurrent lesion in whole body examinations. To our knowledge, there have been no reports of such a solitary metastasis with long DFI.