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A Journal on Diseases of the Respiratory System
Official Journal of the Italian Society of Thoracic Endoscopy
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Minerva Pneumologica 2002 March;41(1):11-4
Our positive experience with LAR octreotide in a case of liver and bone metastases of atypical lung carcinoid
Rossi D., Alessandroni P., Luzi Fedeli S., Fedeli A., Giordani P., Catalano V., Baldelli A. M., Catalano G.
This case report concerns a patient with atypical lung carcinoid with liver and bone metastases successfully treated for over 2 years with LAR octreotide. This patient underwent right bilobectomy with mediastinal adenectomy in 1996. In January 2000, the instrumental evaluation showed a disease progression on liver and bone. After only 1 cycle with cisplatin/etoposide, the patient stopped chemotherapy and started the administration of octreotide LAR (1 i.m. injection every month) for a prolonged sternal pain suspected for angina pectoris. Up to date, this drug allowed to control this neoplasm with no side effects and optimal impact on the patient's quality of life. LAR octreotide is a highly manageable drug and may be used as first approach in this neoplasm, particularly in the elderly or in the presence of clinical impairment.