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A Journal on Diseases of the Respiratory System
Official Journal of the Italian Society of Thoracic Endoscopy
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Minerva Pneumologica 2001 December;40(4):207-12
Acute symmetric acronecrosis during pulmonary tuberculosis. Effetc related to primary disease or to antituberculosis treatment?
Stella N., Catalano A., Pellicciotti A., Udini M.
The case of a 28-year-old male patient who developed a symmetrical acute toe gangrene on both feet during pulmonary tuberculosis is reported. This clinical picture occurred seven days after antituberculosis treatment began. A survey of the literature revealed that these cutaneous lesions, histologically identified as leukocytoclastic vasculitis, have only rarely been reported and that the sensitizing effect of antituberculosis drugs and/or Mycobacterium tuberculosis on microcirculation, represents the possible pathogenic mechanism of this clinical finding.