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A Journal on Diseases of the Respiratory System
Official Journal of the Italian Society of Thoracic Endoscopy
Indexed/Abstracted in: EMBASE, Scopus, Emerging Sources Citation Index
Minerva Pneumologica 2001 March;40(1):41-4
Intrapulmonary sequestration. Congenital or acquired malformations? Two case reports
D'Andrea N., Brozzetti S., Amodio P., Bellotti A., Ruzzetti R., Corsi N., Volpino P.
Pulmonary sequestration is a rare abnormality of the primitive foregut in which part of the lung is separated completely (extralobar) or incompleterly (intralabor) from lung tissue. There is agreement that extralobar seguestration is a congenital anomaly, whereas the pathogenesis of the latter is still controversial. To support both acquired and congenital pathogenesis we report our experience. We describe two unusual cases of intralobar pulmonary sequestration submitted to our observation at the Department of Surgery, University of Rome ''La Sapienza''. The patients underwent surgical resection, the first case presented congenital bronchial abnormality but no evidence of vessel alteration, the second case did not show aberrant arteries or bronchial abnormalities. Because of these findings we wxclude a single pathogenetic hypothesis of intrapulmonary seguestration.