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MINERVA PNEUMOLOGICA

A Journal on Diseases of the Respiratory System


Official Journal of the Italian Society of Thoracic Endoscopy
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Minerva Pneumologica 1999 March;38(1):35-8

language: Italian

Pulmonary tuberculosis in organ transplantation. Description of a clinical case

Corbo E., Tarantino C., Cofano V., Grasso R., Tricarico V.


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In subjects subjected to organ transplantation pulmonary tuberculosis, is a rare infectious complication. The incidence, clinical symptoms, and therapeutic protocols of the tubercular illness in the course of transplantation sre not still well defined. The receiving patients are exposed to a greater risk of tubercular illness because of the immunosuppressive therapy, or the possible presence of mycobacteria in the organs of the donor, or the reactivation of pre-existent endogenous focuses. The case of a patient subjected to liver transplantatio, treated with cyclosporine, presenting pulmonary tubercolosis one year from the intervention is described. The negative interaction of rifampicin on blood cyclosporine, reducing it to therapeutic ineffectiveness values, is proved.

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