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MINERVA PEDIATRICA

A Journal on Pediatrics, Neonatology, Adolescent Medicine,
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Minerva Pediatrica 2015 Sep 10

language: English

Development of a new foetal growth curve from a large sample of italian population

Ferrazzani S. 1, Degennaro V. A. 1, Di Stasio E. 2, Poppa G. 3, Moresi S. 1 , Salvi S. 1, Lanzone A. 1, De Carolis S. 1

1 Department of Obstetrics and Gynaecology and Paediatrics, Catholic University of Sacred Heart, Rome, Italy;
2 Institute of Biochemistry and Clinical Biochemistry, Catholic University of Sacred Heart, Rome; Italy;
3 Department of Obstetrics and Gynaecology, S. Anna University Hospital, Turin, Italy


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OBJECTIVE: Intrauterine growth curves are considered an essential instrument in prenatal medicine for an appropriate auxological classification of foetuses and they have a great importance in clinical practice. Nowadays, in Italy a national curve published in 1975, is the most used. It’s based on birth weights of 8458 newborns from physiological pregnancies. The aim of the present study is to develop a modern foetal growth curve based on accurately selection of 35 240 physiological singleton Italian pregnancies with sure gestational age confirmed by ultrasound.
METHODS: This is a retrospective analysis of 35 240 pregnancies from “A. Gemelli” University Hospital in Rome and "S. Anna" University Hospital in Turin from January 2001 to December 2006. Non-resident pregnant women or coming from other countries, women with diabetes, hypertensive disorders of pregnancy, multiple pregnancies, foetuses with major malformations and /or chromosomal disorders and stillborn foetuses were excluded.
RESULTS: An increasing trend of median neonatal weight, in comparison that with the previous Italian National Curve drawn up in 1975, was found.
CONCLUSIONS: Combining data from two centres, a new foetal growth curve, in which the 10th and the 90th percentiles are clinically reliable, was performed, in order to have a better tool to evaluate the Italian foetal population. A trend towards an increase of birth weight was observed if compared to previous growth curve drawn up more than 30 years ago.

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moresisascia@hotmail.it