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Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,532
Online ISSN 1827-1715
Cardile S., Alterio T., Arrigo T., Salpietro C.
Department of Pediatric Sciences, University of Messina, Messina, Italy
The increasing knowledge about the composition and activities of the microflora have shown the close link between the bacteria and the health of the human organism, for this reason it has focused attention on the possibility of modulating the gut flora. The use of probiotics and prebiotics has increased enormously in recent years, more than for real beneficial effects demonstrated in patients, as for their safety profiles, however, guarantee an indiscriminate use also in conditions in which there are no scientific evidence to support. Although it must be very careful in their use in case of immunocompromised patients or with severe and debilitating chronic diseases for the risk of complications including sepsis. The use of a probiotic can not ignore the knowledge of the genus and species of the strain and in pediatric patients has been demonstrated their role for treating acute viral gastroenteritis and preventing antibiotic-associated diarrhea in healthy children. Moreover probiotics are considered as an option for recurrent and relapsing antibiotic sensitive pouchitis and in select patients with mild ulcerative colitis. Further studies are needed to evaluate clinical conditions that may require their use and to define the optimal doses and intake durations.