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MINERVA PEDIATRICA

A Journal on Pediatrics, Neonatology, Adolescent Medicine,
Child and Adolescent Psychiatry


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Minerva Pediatrica 2017 August;69(4):314-25

DOI: 10.23736/S0026-4946.17.04899-X

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: English

Perioperative factors influencing neurocognitive outcomes in infants

Mary E., McCANN

Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children’s Hospital and Harvard Medical School, Boston, MA, USA


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Neonates have a higher perioperative mortality risk largely due to the premorbid state of the infants and the complex nature of many of the surgeries. Another contributing factor is the rapidly changing physiology of neonates especially during the first 3 days of life. The perioperative management of these critically ill neonates may affect their cerebral perfusion and ultimately neurocognitive outcomes. This article discusses perioperative techniques to maximize cerebral perfusion.


KEY WORDS: Anesthesia, general - Infant, newborn - Infant, premature - Brain ischemia - Blood pressure - Hypocapnia

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Publication History

Issue published online: June 7, 2017
Article first published online: May 3, 2017

Cite this article as

McCann ME. Perioperative factors influencing neurocognitive outcomes in infants. Minerva Pediatr 2017;69:314-25. DOI: 10.23736/S0026-4946.17.04899-X

Corresponding author e-mail

mary.mccann@childrens.harvard.edu