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A Journal on Pediatrics, Neonatology, Adolescent Medicine,
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Minerva Pediatrica 2013 December;65(6):575-85

language: English

Fever and rash in children: important diagnostic considerations

Gurion R. 1, Sabella C. 2, Zeft A. S. 3

1 Pediatric Rheumatology Fellow, Rainbow Babies and Children’s Hospital Cleveland, OH, USA;
2 Pediatrics, Center for Pediatric Infectious Diseases, Cleveland Clinic Children’s, Cleveland, OH, USA;
3 Pediatric Institute, Division of Rheumatology The Cleveland Clinic, Cleveland, OH, USA


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The association of fever with illness has been known for years. A febrile child may have rash, and physicians need to know when this symptom combination is a benign versus a pathologic clinical presentation. In other terms, potential etiologies are either infectious or non-infectious. With scrupulous, methodical history taking and careful, serial physical examination, the treating physician will find hints to assess and solidify an appropriate diagnosis, and chose an appropriate treatment.

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zefta@ccf.org