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A Journal on Pediatrics, Neonatology, Adolescent Medicine,
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Minerva Pediatrica 2011 April;63(2):93-8

language: English

Increased incidence of esophageal atresia in northwest Tuscany: years 1994-2007

Ceccatelli G., Betti M., Vuerich M., Candido G., Moscuzza F., Boldrini A., Ghirri P.

Division of Neonatology and Neonatal Intensive Care Unit, S. Chiara Hospital, University of Pisa, Pisa, Italy


AIM: Esophageal atresia (EA) and imperforate anus are congenital disorders with an incidence that ranges between 1/4000 and 1/5000 births. The aim of this work was to assess the incidence of these malformations in northwest Tuscany and the associated anomalies in comparison with the data published by the Tuscan Congenital Diseases Registry.
METHODS: A retrospective study was made analyzing the cases of these malformations in the years 1994-2007 on a total of 25051 births at the Division of Neonatology of S. Chiara Hospital, Pisa.
RESULTS: The authors found 14 cases of EA and 5 cases of imperforate anus. In these case histories of EA and imperforate anus the incidence was 1/1800 and 1/5000 respectively in comparison with the data issued by the Tuscan Congenital Diseases Registry with an incidence of 1/6644 and 1/4403 in all Tuscany. Five cases of EA (36%) and 2 cases of imperforate anus (40%) were associated with other congenital malformations.
CONCLUSION: Our retrospective study shows a higher incidence of EA in northwest Tuscany than in all the rest of Tuscany unlike the incidence of imperforate anus that it is the same of the rest of Tuscany. In both cases isolated form is most frequent than syndromic one.

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