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A Journal on Pediatrics, Neonatology, Adolescent Medicine,
Child and Adolescent Psychiatry

Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,532

Frequency: Bi-Monthly

ISSN 0026-4946

Online ISSN 1827-1715


Minerva Pediatrica 2009 April;61(2):231-36


Splenic lymphangiomatosis associated with skeletal involvement (Gorham’s disease): a new case and review of literature

Barbagallo M. 1,2, Incorpora G. 3, Magro G. 4, D’Amico S. 5, Pavone V. 6

1 Department of Paediatrics, University of Catania, Catania, Italy
2 Department of Paediatrics, Gravina e Santo Pietro Hospital, Caltagirone, Catania, Italy
3 Department of Paediatrics, Maria Paternò Arezzo Civil Hospital, Ragusa, Italy
4 Department G. F. Ingrassia Pathological Anatomy, University of Catania Catania, Italy
5 Orthopedic Division Department of Medical Surgical Science University of Catania, Catania, Italy

Lymphangiomatosis is a well-recognized congenital benign tumour, frequently seen in infancy and childhood, characterized by the presence of multiple lymphangiomas. Diffuse lymphangiomatosis also involving bony tissue is called Gorham’s disease. This condition generally affects somatic soft tissue, where lymphatics are normally found. A predilection of this affection for bone, thoracic and neck involvement is well known, while involvement of abdominal viscera is very unusual. In bone this non malignant proliferation of lymphatic channels results in destruction and resorption of the osseous matrix. We report on a child in whom lymphangiomatosis involved both the bone and the spleen. A review of 166 cases is also reported.

language: English


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