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MINERVA PEDIATRICA

A Journal on Pediatrics, Neonatology, Adolescent Medicine,
Child and Adolescent Psychiatry


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Minerva Pediatrica 2009 February;61(1):119-22

language: English

Primary Sjögren’s syndrome mimicking lymphoma in a pediatric patient. A rare and possibly misdiagnosed condition

Buonuomo P. S. 1, Maurizi P. 2, Bracaglia C. 1, Margani G. 2, Riccardi R. 2

1 Department of Pediatric Medicine Division of Pediatric Rheumatology “Bambino Gesù” Pediatric Hospital, Rome, Italy
2 Department of Pediatrics, Pediatric Oncology Sacro Cuore Catholic University “A. Gemelli” Policlinic, Rome, Italy


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A 12-year-old girl presented at the Oncoemato-logic Department with an acute onset of generalized lymphadenopathy. Lymphoproliferative disorders were highly suspected. Biopsied cervical and inguinal lymph node disclosed neither malignant cells nor monoclonal proliferation of lymphocytes. Revaluating the diagnosis, anamnestic data revealed multiple episodes of bilateral parotid swelling since age one, without systemic symptoms. Laboratory investigations, parotid ecography, Schirmer test revealed Sjogren’s syndrome without associated disease. Sjogren syndrome (SS) in childhood is a rare and possibly underdiagnosed condition.

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