Home > Journals > Minerva Pediatrica > Past Issues > Minerva Pediatrica 2008 August;60(4) > Minerva Pediatrica 2008 August;60(4):457-60

CURRENT ISSUE
 

ARTICLE TOOLS

Reprints

MINERVA PEDIATRICA

A Journal on Pediatrics, Neonatology, Adolescent Medicine,
Child and Adolescent Psychiatry


Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,532


eTOC

 

CASE REPORTS  


Minerva Pediatrica 2008 August;60(4):457-60

Idiopathic infantile arterial calcification: case report

Palmas G. 1, Tumbarello R. 2, Abbruzzese P. 3, Fanos V. 1

1 Neonatal Intensive Care Unit University of Cagliari, Cagliari, Italy
2 Department of Pediatric Cardiology Brotzu Hospital, Cagliari, Italy
3 CUORE Department Children’s Hospital Regina Margherita, Turin, Italy


PDF  


Idiopathic infantile arterial calcificationI (IIAC) is a rare disorder characterized by calcium deposition in the internal elastica lamina of medium and large arteries and it has been defined in term of molecular genetics. It is usually fatal, approximately 85% of all patients die within the first months of life owing to ischemia of vital organs. Death from myocardial infarction usually occurs in the first 6 months. Calcification in a peripheral artery with electrocardiogram (ECG) changes of occlusive coronary artery disease suggests the diagnosis. It is caused by mutations in the ENPP1 gene localized on chromosome 6q22 and has OMIM number 208000. A case with fatal evolution at the end of the first month is presented.

top of page

Publication History

Cite this article as

Corresponding author e-mail