Home > Journals > Minerva Pediatrica > Past Issues > Minerva Pediatrica 2008 June;60(3) > Minerva Pediatrica 2008 June;60(3):343-6

CURRENT ISSUE
 

ARTICLE TOOLS

Reprints

MINERVA PEDIATRICA

A Journal on Pediatrics, Neonatology, Adolescent Medicine,
Child and Adolescent Psychiatry


Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,532


eTOC

 

REVIEWS  


Minerva Pediatrica 2008 June;60(3):343-6

language: English

Noonan syndrome. A review

Cesur Aydin K., Ozcan I..

Faculty of Dentistry, University of Istanbul Department of Oral Diagnosis and Radiology, Fatih, Istanbul, Turkey


PDF  


Noonan syndrome (NS) is a rare genetic disorder, revealing autosomal dominant trait. It is a multiface condition that is characterized by a series congenital malformations including facial anomalies, postnatal growth retardation, webbing of the neck, pectus excavatum/carinatum, pulmonic stenosis and undescended testicles in boys. The incidence of NS is estimated to be between 1:1 000 and 1:2 500 in all live births. A DNA test for mutation analysis can be carried out on blood, chorionic villi and amniotic fluid samples. Signs and symptoms lessen with age and most adults with NS do not require special medical care.

top of page

Publication History

Cite this article as

Corresponding author e-mail