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A Journal on Pediatrics, Neonatology, Adolescent Medicine,
Child and Adolescent Psychiatry

Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,532

Frequency: Bi-Monthly

ISSN 0026-4946

Online ISSN 1827-1715


Minerva Pediatrica 2007 April;59(2):85-9


Noninvasive ventilation with positive airway pressare in paediatric intensive care

Ottonello G. 1, Villa G. 2, Doglio L. 3, Pedemonte M. 3, Diana M. C. 2, Casciaro R. 4, De Alessandri A. 4, Silvestri G. 1

1 Unit of Anesthesia and Intensive Care G. Gaslini IRCCS, Genoa, Italy
2 Emergency Unit, G. Gaslini IRCCS, Genoa, Italy
3 Department of Neurosciances and Rehabilitation G. Gaslini IRCCS, Genoa, Italy
4 Regional Center on Cystic Fibrosis Department of Pediatrics University of Genoa, Genoa, Italy

Aim. The aim of the present study is to retrospectively evaluate the effectiveness of noninvasive pressure ventilation in the 24-bed Pediatric Intensive Care Unit (PICU) of the G. Gaslini Institute during a 24-month period.
Methods. A retrospective analysis of the characteristics (pH, CO2, SpO2, respiratory rate, oxygen requirement) of patients treated with noninvasive mechanical ventilation for different acute pathologies has been performed.
Results. Twenty patients (mean age 7.4±0.28 years) with acute respiratory failure due to different pathologies were treated with noninvasive mechanical ventilation. They were divided into 2 groups: the hypoxic group, suffering from pulmonary diseases, and the hypercapnic group, presenting a failure of the mechanical strength or increased dead space. Modalities of ventilation were pressure assisted/controlled or pressure support, delivered through nasal or facial masks. Fifteen out of 20 patients presented a marked improvement of oxygenation and ventilation. Mean times of treatment were 69 and 200 h in the hypoxic and hypercapnic groups, respectively. Five patients required intubation. Two patients presented reversible skin lesions over the nasal bridge.
Conclusion. Noninvasive ventilation can be used in PICU. Major advantages regard immunocompromised children and patients with exacerbations from chronic respiratory diseases, whereas the exact role of noninvasive positive pressure ventilation in patients affected by acute respiratory distress syndrome is still controversial.

language: English


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