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Home > Journals > Minerva Pediatrica > Past Issues > Minerva Pediatrica 2006 December;58(6) > Minerva Pediatrica 2006 December;58(6):575-7



A Journal on Pediatrics, Neonatology, Adolescent Medicine,
Child and Adolescent Psychiatry

Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,532

Frequency: Bi-Monthly

ISSN 0026-4946

Online ISSN 1827-1715


Minerva Pediatrica 2006 December;58(6):575-7


QT prolongation and minor head trauma: a report of two cases

Koturoglu G. 1, Kurugol Z. 1, Levent E. 2

1 Department of Pediatrics Faculty of Medicine Ege University, Izmir, Turkey
2 Division of Pediatric Cardiology Department of Pediatrics, Faculty of Medicine Ege University, Izmir, Turkey

QT prolongation is rarely seen after acute stress reactions such as burn injury and severe head trauma. Although pathophysiologic mechanism is not entirely clear, acute stress is thought to contribute to the inhomogeneity of ventricular repolarization and it is hypothesized that QTc dispersion increases with severity of acute stress conditions. In the present study, we report long QT syndrome in 2 patients with minor head trauma. Their QTc intervals, i.e. QT intervals corrected for heart rate by the standard Bazett formula, were found to be prolonged (545 and 450 ms, respectively) without creatine phosphokinase - MB elevation. These findings suggest that myocardial effects may occur as a result of probable catecholamine discharge, even if they are not at a level to affect creatine phosphokinase - MB values in minor head trauma. But these findings have not been supported by experimental data, for this reason we need a lot of study in order to confirm this hypothesis.

language: English


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