Advanced Search

Home > Journals > Minerva Ortopedica e Traumatologica > Past Issues > Minerva Ortopedica e Traumatologica 2016 June;67(2) > Minerva Ortopedica e Traumatologica 2016 June;67(2):75-8

ISSUES AND ARTICLES   MOST READ   eTOC

CURRENT ISSUEMINERVA ORTOPEDICA E TRAUMATOLOGICA

A Journal on Orthopedics and Traumatology

Official Journal of the Piedmontese-Ligurian-Lombard Society of Orthopedics and Traumatology
Indexed/Abtracted in: EMBASE, Scopus, Emerging Sources Citation Index

Ferquency: Quarterly

ISSN 0026-4911

Online ISSN 1827-1707

 

Minerva Ortopedica e Traumatologica 2016 June;67(2):75-8

    ORIGINAL ARTICLES

Clinical usefulness of oral supplementation with curcumin phytosome in patients with radiculopathy due to spondyloarthritis or discopathy

Giuseppe MAIDA

Department of Surgery, Division of Spine Surgery, S. M. Maddalena Hospital, S. M. Maddalena-Rovigo, Italy

BACKGROUND: The aim of this study was to explore the efficacy and safety of curcumine phytosome (Meriva®) in reducing the pain due to radiculopathy, in patients affected with spine arthritis or discopathy.
METHODS: Thirty-six patients affected with radiculopathy seen in one Italian neurosurgical outpatients facility, were enrolled to participate in an open, not controlled study, and were treated with curcumine phytosome for 100 days. Pain, motor functionality and other symptoms were assessed at baseline, 50 and 100 days.
RESULTS: There was a marked reduction in pain rating, statistically significant both at 50 and 100 days from baseline. The reduction was statistically significant, both in the intention-to-treat population and in the observed cases. A mild, not clinically significant, reduction in motor functionality was observed at day 50 but not at day 100. No adverse events were recorded.
CONCLUSIONS: This exploratory study highlights the clinical usefulness of curcumine phytosome long term treatment of pain due to radiculopathy, due from spine arthritis or discopathy.

language: English


FULL TEXT  REPRINTS

top of page