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A Journal on Orthopedics and Traumatology

Official Journal of the Piedmontese-Ligurian-Lombard Society of Orthopedics and Traumatology
Indexed/Abtracted in: EMBASE, Scopus, Emerging Sources Citation Index

Ferquency: Quarterly

ISSN 0026-4911

Online ISSN 1827-1707


Minerva Ortopedica e Traumatologica 2014 February;65(1):61-72


Nutraceuticals and chondroprotective agents for the treatment of osteoarthritis: a narrative review. A controversial resource in the treatment of osteoarthritis

Sansone V. 1, 2, Consonni O. 1, 2, Maiorano E. 1, 2

1 Orthopaedic Department University of Milan, Milan, Italy;
2 Istituto Ortopedico Galeazzi IRCCS, Milan, Italy

There are many dietary supplements, chondroprotective agents, disease-modifying agents and nutraceuticals that have been developed and promoted for treating patients affected by osteoarthritis (OA). They can be, and often are, marketed without undergoing a rigorous scientific evaluation. In the literature several in vitro- or in vivo-trials concerning these compounds can be found, but there is a lack of high-quality, long-term, prospective, comparative studies able to demonstrate unequivocally their effectiveness in the treatment of OA. This is a narrative review concerning the commonest chondroprotective agents found on the market, and assesses whether, on the basis of the current literature, these agents may have a role in the treatment of OA.

language: English


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