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MINERVA ORTOPEDICA E TRAUMATOLOGICA
A Journal on Orthopedics and Traumatology
Minerva Ortopedica e Traumatologica 2013 June;64(3):341-6
Efficacy and safety assessment of hyaluronic acid injection for hip osteoarthritis: experience in the Azienda Ospedaliera Città della Salute e della Scienza, Torino
Celani R. 1, Parisi S. 2, Caviglia S. 1, Laganà A. 2, Ruggieri N. 1, Fusaro E. 2 ✉
1 S.C. Ortopedia e Traumatologia , A.O.U. San Giovanni Battista di Torino;
2 S.C. Reumatologia , A.O.U. San Giovanni Battista di Torino
Aim: The aim of this study was to evaluate the long-term efficacy and tolerability of ultrasound-guided intra-articular hyaluronic acid injection in patients with symptomatic hip osteoarthritis.
Methods: The study population was 62 patients with osteoarthritis selected according to the American College of Rheumatology criteria. Patients received 2 ml (32 mg/2 ml) mid-to-high-molecular-weight (800-1200 kDa) biofermented hyaluronic acid and were monitored for 12 months following intra-articular injection.
Results: Treatment was assessed by means of a visual analogue scale (VAS) and use of non-steroid anti-inflammatory drugs (NSAIDs). An improvement in pain as measured by changes in VAS scores was observed at 6 months in all patients (100%), with a mean reduction of 45.20%. Improvement in VAS pain scores was unchanged at 12 months in 32 patients (P=0.007). A significant reduction in the use of NSAIDs was noted at 6 months in all patients and a reduction of 40% in NSAIDs at 12 months in all patients.
Conclusion: The efficacy and tolerability of this treatment indicate that ultrasound-guided intra-articular hyaluronic acid injection may be offered to the majority of patients with hip osteoarthritis.