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MINERVA ORTOPEDICA E TRAUMATOLOGICA
A Journal on Orthopedics and Traumatology
Minerva Ortopedica e Traumatologica 2006 April;57(2):57-63
Therapy of discoradicular conflict. Compa-rison between paravertebral oxygen-ozone therapy and combination of oxygen-ozone therapy and a product containing alfa-lipoic acid (ALAnerv®)
Vetro A., Mantia F., Mantia R.
Centro Medico Mantia Presidio Ambulatoriale di Recupero e Riabilitazione Funzionale, Palermo
Aim. Aim of this retrospective study has been the comparison between the oxygen-ozone therapy alone and the oxygen-ozone therapy (OOT) combined to the administration of a product containing a lipoic acid and g linolenic acid (ALAnerv®) for the treatment of lumbar and/or cervical discoradicular conflicts in order to assess eventual differences in the clinical efficacy in terms of pain and inability decreasing.
Methods. 198 subjects afferent to our centre between the years 2003 and 2004 with a diagnosis of lumbar and/or cervical discoradicular conflicts treated with OOT alone (Group 1: 81 subjects corresponding to 41%) or OOT plus administration of ALAnerv® (Group 2: 117 subjects corresponding to 59%), have been selected. The scores obtained by the visual analogic scale (VAS) have been considered for the assessment of pain while the assessment of inability grade has been done according Barthel index. The comparisons have been performed within group and between groups at each planned visits (post-treatment, 11 weeks, 19 weeks) and they have been analysed by Wilcoxon test for paired data and by Mann-Whitney test.
Results. All the performed comparisons have been resulted statistically significant (P<0.001). The analyses evidence that the decrease of VAS score is mostly statistically significant in the group who took ALAnerv®. The same trend can be observed for the evaluation of inability grade.
Conclusion. The treatment oxygen-ozone therapy associate to the administration of ALAnerv® results to be more valid than oxygen-ozone therapy alone, for solving the problem of discoradicular conflict in a rapid, minimally invasive and lasting way.