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MINERVA ORTOPEDICA E TRAUMATOLOGICA
A Journal on Orthopedics and Traumatology
UPDATES ON HIP ARTHROPLASTY 102nd CONGRESS OF THE PIEMONTESE-LIGURIAN-LOMBARD SOCIETY OF ORTHOPEDICS AND TRAUMATOLOGY (S.P.L.L.O.T.) - Brescia September 9-10, 2005
NEW TECHNOLOGIES, MODERN INSTRUMENTARIUM IN ARTHROPLASTIC SURGERY
Minerva Ortopedica e Traumatologica 2005 August;56(4):209-14
The use of growth factors in prosthesis revision: preliminary results and review of the literature
D’Imporzano M., de Bellis U., Fadigati P., Tagliabue L., Pierannunzii L.
Terza Divisione/CAD Istituto Ortopedico Gaetano Pini, Milano
Aim. The article gives an overview of the literature on the use of growth factors in orthopedics, with special attention to prosthesis revision, and an analysis of preliminary results of a study the authors conducted in this area.
Methods. Revision of hip replacement with homologous grafts was performed in 12 patients (4 men, 8 women; mean age, 64 years; range, 53-74). The mean survival of the prosthesis was 9 years (range, 6-14).
Results. The partial results refer to a mean follow-up of 8-9 months. Iconographic control examinations performed at 40, 90 and 180 days postoperative appeared to show greater bone integration of the acetabular cup and the grafts, associated with augmented and accelerated appositional bone growth, as determined by enlarged radiographic imaging at 90 days, in the group that received growth factors versus the group that received only homologous grafts.
Conclusion. Although partial, our preliminary data show greater and faster bone integration of grafts, as measured by radiographic documentation and clinical examination, with the use of growth factors.