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MINERVA ORTOPEDICA E TRAUMATOLOGICA
A Journal on Orthopedics and Traumatology
BIOMATERIALS IN ORTOPEDICS: EXPECTATION AND CLINICAL PRACTICE 96° CONGRESS OF THE PIEDMONTESE-LIGURIAN-LOMBARD SOCIETY OF ORTHOPEDICS AND TRAUMATOLOGY (SPLLOT) (Brescia, September 24-25, 1999)
Minerva Ortopedica e Traumatologica 2000 June;51(3):107-12
The role of hydroxyapatite in osseointegration. Preliminary results of a randomized prospective study
De Santis E., Gasparini G., Romanini E., De Santis V.
Hydroxyapatite-coated femoral stems have been used for about ten years in clinical practice. The role played by HA-coating was analyzed in detail both experimentally and with implants retrieved at autopsy, but only a few randomized controlled studies have been published. The authors present the preliminary results of a trial designed to evaluate the same straight stem, porous versus HA coated, random applied in a series of 80 patients affected by osteoarthritis. Radiographic findings showed earlier and higher rate of osseointegration in the HA-coated group, however no significant differences were observed comparing patient-oriented (generic and disease specific) and physician derived scores. Prospective analysis of the two groups will eventually define the influence of different coatings on the quality of life of the patients, as well as on the survival rates of the implant.