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Minerva Oftalmologica 2012 March;54(1):35-8

Copyright © 2012 EDIZIONI MINERVA MEDICA

language: Italian

Iridocorneal-endothelial syndrome: diagnosis and main treatments

Comune B. 1, 2, Comune C. 3

1 Specialista ambulatoriale, Unità di Oftalmologia ASL NA 2 NORD DS n.45, Napoli, Italia; 2 Libero professionista, Napoli, Italia; 3 Laureata in Medicina e Chirurgia


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Iridocorneal-endothelial syndrome (ICE syndrome) is a disease of the ocular anterior segment characterized by a “hammered-silver” appearance of the corneal endothelium, corneal failure, glaucoma, and iris destruction. ICE syndrome is actually a grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome; Chandler’s syndrome; and progressive iris atrophy. Our review aims to collect the various etiopathogenic theories about this syndrome and to describe the main treatment modalities in literature.

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