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A Journal on Ophthalmology
Minerva Oftalmologica 2008 December;50(4):101-5
Hydroxyapatite orbital implants in children after enucleation for retinoblastoma: staging of fibrovascular ingrowth
Hadjistilianou T., De Francesco S., Galluzzi P., Menicacci F., Borri M., De Luca M., Motolese E.
Dipartimento di Scienze Oftalmologiche e Neurochirurgiche Università degli Studi di Siena Policlinico Le Scotte, Siena, Italia
Aim. This study evaluated the utility of magnetic resonance imaging (MRI) when staging fibrovascular ingrowth of hydroxyapatite implants and whether there were differences between patients who received radio- and/or chemotherapy before or after enucleation.
Methods. Between 1995 and 2008, a total of 207 enucleation procedures were performed, and hydroxyapatite orbital implants were positioned in 47 cases. Clinical assessment criteria were: mean age at enucleation, pre- and/or postintervention radio- and/or chemotherapy, degree of implant vascularization, time between enucleation and MRI study, follow-up.
Results. Implant vascularization potential was significantly higher in patients who had not received radio- or chemotherapy.
Conclusion. Implant fibrovascularization is greatest within 6 months after enucleation in patients who do not receive radio- and/or chemotherapy and after 12 months in those who receive pre- and/or postintervention treatment.