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Minerva Oftalmologica 2008 December;50(4):101-5

language: Italian

Hydroxyapatite orbital implants in children after enucleation for retinoblastoma: staging of fibrovascular ingrowth

Hadjistilianou T., De Francesco S., Galluzzi P., Menicacci F., Borri M., De Luca M., Motolese E.

Dipartimento di Scienze Oftalmologiche e Neurochirurgiche Università degli Studi di Siena Policlinico Le Scotte, Siena, Italia


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Aim. This study evaluated the utility of magnetic resonance imaging (MRI) when staging fibrovascular ingrowth of hydroxyapatite implants and whether there were differences between patients who received radio- and/or chemotherapy before or after enucleation.
Methods. Between 1995 and 2008, a total of 207 enucleation procedures were performed, and hydroxyapatite orbital implants were positioned in 47 cases. Clinical assessment criteria were: mean age at enucleation, pre- and/or postintervention radio- and/or chemotherapy, degree of implant vascularization, time between enucleation and MRI study, follow-up.
Results. Implant vascularization potential was significantly higher in patients who had not received radio- or chemotherapy.
Conclusion. Implant fibrovascularization is greatest within 6 months after enucleation in patients who do not receive radio- and/or chemotherapy and after 12 months in those who receive pre- and/or postintervention treatment.

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