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A Journal on Ophthalmology
Minerva Oftalmologica 2006 March;48(1):1-3
Evolution of visual field decline in patients affected from retinitis pigmentosa with different genetic trasmission
Rossi S., Catapano A., Maggio E., D’Acunzo T., de Benedictis A., Testa F.
Dipartimento di Oftalmologia Seconda Università degli Studi di Napoli, Napoli
Aim. Retinitis pigmentosa is a clinically haeterogenous group of retinal degenerations that are caracterised by nigthblindess, progressive loss of peripheral vision and pigmentary alterations in the retina. Based on the genetic origin, are distinguished X-linked shapes of Retinitis Pigmentosa, autosomic recessive shapes, autosomic dominant shapes and sporadic shapes. Objective: to evaluate the rate of declineof visual field area in patients with Retinits pigmentosa and the correlation between the progression of field loss and different genetic subtypes of RP.
Methods. We studied the clinical behavior of 251 patient with RP. A genetic advising was made in order to identify the trasmission models.
The patients have been examinated for three years at least.
Results and conclusions. Average rate of field loss did not vary significatly in patients with autosomic dominant and sporadic RP; in contrast it was faster in patients with autosomic recessive RP.