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A Journal on Ophthalmology
Minerva Oftalmologica 2005 September-December;47(3-4):129-36
Immunosuppressive therapy in uveitis
Paroli M. P., Pivetti Pezzi P.
Immunosuppressive drugs represent a large and heterogeneous group of molecules united by the property of interfering with the immune system's capability of activation and response, and are widely used in autoimmune diseases. Their use in uveitis aims at allowing adequate inflammation control and reduced toxicity related to the use of corticosteroids. Due to potential side effects, immunosuppressive treatments must be individualized and regular monitoring performed with the immunologist, and, if necessary, in cooperation with colleagues of other specialities. Recently, a number of new substances have been introduced in clinical practice and, in the near future, a further therapy perfectioning is auspicable because, at present, the potential of toxic effects and high costs limit their use.