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A Journal on Ophthalmology
Minerva Oftalmologica 2000 September-December;42(3-4):47-50
Chromium, nicotinic acid, vitamins P and C: effects of their association on perimetric indices in myopic patients
Migliorini R., Taverniti L.
Background. To evaluate the effects of an association of chromium, niacin, bioflavonoids and vitamin C on the retina sensitivity of patients with bilateral myopia ranging between-5 and-12 diopters.
Methods. The random comparative study was carried out at the Institute of Ophthalmology of the University of Rome ³La Sapienza². A total of 70 patients were enrolled, including 30 males and 40 females aged between 30 and 55 years old. The patients were divided into two groups: 35 were treated and 35 acted as controls. All patients suffered from bilateral myopia ranging between -5 and -12 diopters, without any other ocular pathologies with visual acuity of less than 6/10, no systemic illnesses that might jeopardise circulatory dynamics (diabetes, severe arteriosclerosis, arterial hypertension). Thirty-five patients were treated for 120 days with an association of chromium (100 mcg), nicotinic acid (24 mg), vitamin P (96 mg) and vitamin C (80 mg); 35 patients were not treated and were used as controls. The following tests were performed prior to treatment and at the end: visual acuity, visual field using automatic perimetrics (Humphrey 750, prog. 30.2), ocular tone using applanation tonometrics, ocular fundus using indirect retinoscopy.
Results. A statistically significant reduction was achieved in the treated group in the two perimetric indexes used (MD and PSD) correlated with age, the degree of myopia and the starting value of short-term fluctuation, whereas foveolar value, visual acuity and ocular tone did not alter significantly.
Conclusions. The use of this association is suggested in the tratment of myopic patients with damaged retina function.