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Minerva Oftalmologica 1999 March;41(1):35-48

language: Italian

Therapeutic value of magnesium-arginine association with extract of Gingko biloba in the treatment of microcirculation dynamics in retinal arteriosclerosis

Salducci M., Lorini A., Balacco Gabrieli C.


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Background and aim. The authors evaluated the therapeutic value of the association of magnesium-arginine with an extract of Gingko biloba in alterations to the dynamics of the retinal microcirculation.
Methods. The prospective study lasted ninety days. Tests were carried out at the general clinic of the 2nd Ophthalmology Division of the Institute of Ophthalmology‹Policlinico Umberto I‹Rome, and participants in the study underwent a general ophthalmological check-up after which they performed electrophysiological tests and campimetric analysis. A total of 30 patients were enrolled in the study aged between 58 and 71 years old. All showed ophthalmoscopic signs of arteriosclerotic retinopathy. All patients enrolled completed the study. Treatment consisted in taking two tablets/day for 90 days containing an association of magnesium-arginine with an extract of Gingko biloba. Measurements were made at the start of the study, forty-five days after treatment and three months after treatment. Visual performance was evaluated using objective and subjective tests.
Results. Eyes with poor correct visus (5-7/10) showed the highest percentage of improvement in terms of visual acuity, confirmed by increased retinal sensitivity measured using computerised campimetry in 25% of the population examined.
Conclusions. The use of a magnesium-arginine association with Gingko biloba extract in ophthalmology is certainly worth studying in greater detail in view of the results obtained in the treatment of chronic retinal vasculopathies.

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