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Minerva Medicolegale 2006 June;126(2):207-11

Copyright © 2006 EDIZIONI MINERVA MEDICA

language: Italian

Biological markers in chemical-toxicological alcohol abuse tests

Zacà S. 1, Pellegrino S. 2, Petrarulo M. 2

1 S.O.C.D.U. Medicina Legale Ospedale Gradenigo, Torino 2 Settore di Tossicologia, Laboratorio Analisi Ospedale Mauriziano, Torino


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Habitual alcohol use and/or abuse can be detected with a series of diagnostic markers that correlate with the clinical picture. Multiple indicators are required for accurate determination because individual test parameters are unspecific, often leading to different, contradictory results. The authors suggest the systematic use of a novel biological marker, ethyl ‚-D-6-glucuronic acid, which has been widely tested in specialized centers. This metabolite correlates directly with the amount of alcohol intake and can be detected in the urine up to 80 hr after the last drink or in the hair in cases of habitual alcohol consumption.

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