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Minerva Medica 2003 June;94(3):187-90

Copyright © 2003 EDIZIONI MINERVA MEDICA

language: English

Febrile pancytopenia and psychosis revealing pernicious anemia

Alliot C., Durigon F., Barrios M.


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The rare case of a 42-year-old woman of African origin presenting with persecution mania leading to admission to a psychiatric hospital is reported. The outcome was rapidly marked by febrile pancytopenia and ataxia leading to the diagnosis of pernicious anemia. Although the hematologic abnormalities and mania were corrected within 2 weeks under vitamin therapy, neural improvement was slower as observed classically. The literature regarding pancytopenia and psychiatric presentations is briefly reviewed, suggesting that vitamin B12 deficiency may induce paranoid delusion.

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