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Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,236
Online ISSN 1827-1669
Trifiletti A., Scamardi R., Cincotta M., Sottilotta G., Gaudio A., Romano C., Sottile L., Lasco A.
Background. The aim of this study was to evaluate wheter a family history of hypertension is associated with haemostatic disorders.
Methods. In 38 normotensive subjects with a family history of hypertension (relatives) and in 46 sex, age and body mass index matched controls with no family history of hypertension, tissue-type plasminogen activator (t-PA), plasminogen activator-inhibitor (PAI-1), D-dimer (DD) and prothrombin fragment 1+2 (F1+2) were evaluated. Results. The t-PA and PAI-1 observed values were significantly higher than the values detected in the controls.
Conclusions. These data seem to suggest a correlation between family history of hypertension and haemostatic disorders.