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A Journal on Internal Medicine
Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,236
Minerva Medica 2001 February;92(1):19-22
Correlation between family history of hypertension and haemostatic disorders
Trifiletti A., Scamardi R., Cincotta M., Sottilotta G., Gaudio A., Romano C., Sottile L., Lasco A.
Background. The aim of this study was to evaluate wheter a family history of hypertension is associated with haemostatic disorders.
Methods. In 38 normotensive subjects with a family history of hypertension (relatives) and in 46 sex, age and body mass index matched controls with no family history of hypertension, tissue-type plasminogen activator (t-PA), plasminogen activator-inhibitor (PAI-1), D-dimer (DD) and prothrombin fragment 1+2 (F1+2) were evaluated. Results. The t-PA and PAI-1 observed values were significantly higher than the values detected in the controls.
Conclusions. These data seem to suggest a correlation between family history of hypertension and haemostatic disorders.