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A Journal on Obstetrics and Gynecology

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Minerva Ginecologica 2013 February;65(1):79-88

language: English

Efficacy of a topical cosmetic slimming treatment for postmenopausal women: a randomized, double-blind, placebo controlled trial

Pluchino N. 1, Santoro A. N. 1, Sparavigna A. 2, Vesnaver R. 3, Cenni A. 4, Oliva M. 4, Genazzani A. R. 1

1 Division of Gynecology and Obstetrics, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy;
2 Derming, Clinical Research and Bioengineering Institute, Monza, Milan, Italy;
3 Oikos Srl, Milan, Italy4Società Italo Britannica L. Manetti - H. Roberts & C. per Azioni, Calenzano, Florence, Italy


Aim: The aim of this paper was to evaluate by clinical and non-invasive instrumental evaluations under dermatological control, the efficacy and the tolerance of a cosmetic slimming treatment for menopausal women (since at least 3 years) used topically.
Methods: A controlled double blind, randomised study was performed to compare the slimming efficacy of the cosmetic slimming treatment versus placebo after 4 weeks of treatment.
Results: Cosmetic slimming treatment twice a day for 4 weeks reduced abdomen and hips fat in comparison with the placebo, with no significant variation in body weight.
Conclusion: The present study evidenced the clinical effectiveness and women satisfaction of a slimming treatment specifically studies for postmenopausal adipose tissue with potential interesting consequences on measures of quality of life and on health-care program.

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