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A Journal on Obstetrics and Gynecology
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index
Minerva Ginecologica 2011 June;63(3):213-8
Sex ratio in the offspring of pregnant women with polycystic ovary syndrome: effect of different phenotypes
Palomba S. 1, Falbo A. 1, Rocca M. 1, Albano A. 1, Condorelli M. 1, Mazza R. 1, James J. H. 2, Zullo F. 1 ✉
1 Department of Obstetrics and Gynecology, University “Magna Graecia” of Catanzaro, Catanzaro, Italy;
2 Department of Genetics, Evolution and Environment, University College London, London, UK
AIM: The aim of this paper was to investigate the sex ratio in the offspring of pregnant patients with polycystic ovary syndrome (PCOS).
METHODS: Analysis of 70 pregnant patients with PCOS who achieve a pregnancy without any kind of treatment, and having as controls 63 healthy pregnant women without any feature of PCOS.
RESULTS: No significant difference in sex ratio was detected between PCOS and controls, even if it resulted significantly different in the full-blown and non-PCO phenotypes.
CONCLUSION:The PCOS phenotypes influenced the sex ratio in the offspring, suggesting that environmental factors could play a role in determination of the offspring gender.