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A Journal on Obstetrics and Gynecology
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index
CARDIAC PROBLEMS IN PREGNANCY
Minerva Ginecologica 2010 April;62(2):121-8
A review of thromboembolic complications in pregnancy
Jurus D., Duhl A., Ural S. H.
1 Department of Obstetrics and Gynecology, Pennsylvania State University College of Medicine, Hershey, PA, USA;
2 Department of Obstetrics and Gynecology, Ocean Perinatology, New York, NY, USA;
3 Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology and Radiology, Labor and Delivery Unit
Pennsylvania State University College of Medicine, Hershey, PA, USA
Combined with the enlarging uterus compressing the venous system of the pelvis and the vessel trauma incurred in delivery, an increase in clotting factor production in pregnancy predisposes the gravid patient to the peril of thromboembolism. When a patient has an inherited thrombophilia and becomes pregnant, this combination of risk factors in the presence of pregnancy may be the tipping point, pushing the coagulation cascade into an activated state. All thrombophilias, deep vein thrombosis, and pulmonary embolism are factors associated with complications in pregnancy that may lead to catastrophic consequences. This review report on the most frequent thromboembolic complications in pregnancy.