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A Journal on Obstetrics and Gynecology
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index
Minerva Ginecologica 2008 April;60(2):121-5
Preliminary evaluation of a vaginal cream containing lactoferrin in the treatment of vulvovaginal candidosis
Costantino D. 1, Guaraldi C. 2
1 Centro Salute Donna, Azienda USL, Ferrara, Italia
2 Reparto di Ostetricia e Ginecologia, Ospedale di Valdagno, Valdagno, Vicenza, Italia
PRELIMINARY EVALUATION OF A VAGINAL CREAM CONTAINING LACTOFERRIN IN THE TREATMENT OF VULVOVAGINAL CANDIDOSIS
Aim. The objective of the study is to verify the clinical effectiveness of a cream containing lactoferrin in the treatment of acute vulvovagininal candidiasis.
Methods. The study enrolled 34 patients aged 25-45 years and preenting signs and symptoms of acute vulvovaginal candidiasis. The patients have been treated with a cream containing lactoferrin 4%, 5 g of cream in vagina and 2 cm applied on the vulva twice a day for 7 days. At the end of the treatment the patients a clinical and microscopical examination was performed in order to evaluate the effectiveness of the therapy.
Results. The results obained showed that 27 women completely recovered, 5 showed a good improvement and only 2 women were still suffering from vulvovaginitis at the end of treatment.
Conclusion. From the data of our study, a cream containing lactoferrin seems to be clinicalIy effective in the treatment of acute vulvovaginal candidiasis, with a good response on all the characteristic symptoms of this infection.