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A Journal on Obstetrics and Gynecology

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Minerva Ginecologica 2007 October;59(5):499-504

language: Italian

Endometrial ablation versus hysterectomy in women treated with tamoxifen

Capuano I. 1, Caporale A. 2, Vagnetti P. 1, Di Domenico A. 1, Felicetti M. 1, Torella M. 1, Borrelli A. L. 1

1 Dipartimento di Scienze Ginecologiche Ostetriche e della Riproduzione, Seconda Università degli Studi di Napoli, Napoli, Italia
2 Divisione Ginecologia Ostetricia, Ospedale Santa Maria del Popolo degli Incurabili, Napoli, Italia


Aim. The aim of our study is the assessment of the importance of the endometrial ablation versus hysterectomy in patients treated with tamoxifen for previous breast cancer.
Methods. Fifty-eight outpatients in therapy with tamoxifen for 1 year were controlled in the Department of Gynaecology of the University of Naples. We have selected these patients in two groups: group A, with 28 women with abnormal uterine bleeding and endometrial thickness >8 mm and group B, with 30 normal endometrium asintomatic women. All patient of group A and 18 of group B were treated with endometrial ablation.
Results. Next follow-up showed normal hysteroscopy figures in 89% of cases and 5% of cases needed a hysterectomy for new abnormal uterine bleeding and cytology.
Conclusion. Our results show the utility of endometrial ablation especially in selected cases in therapy with tamoxifen for previous breast cancer.

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