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A Journal on Obstetrics and Gynecology
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index
Minerva Ginecologica 2007 April;59(2):111-6
Laparoscopic lymphadenectomy as treatment of endometrial cancer
Morelli M., Noia R., Costantino A., Chiodo D., Mocciaro R., Caruso M., Cosco C., Lucia E., Curcio B., Gullì G., Amendola G., Zullo F.
Dipartimento di Medicina Sperimentale e Clinica Facoltà di Medicina e Chirurgia, Cattedra di Ginecologia e Ostetricia, Università degli Studi di Catanzaro,
“Magna Græcia”, Catanzaro, Italia
Aim. This study compares the effects of laparoscopic lymphadenectimy versus those of abdominal lymphadenectomy in patients with endometrial cancer.
Methods. A prospective randomized study was performed among 80 patients randomly assigned to laparoscopic lymphadenectomy and to abdominal lymphadenectomy in the treatment of endometrial cancer. Clinical outcomes and complications were compared for 1 year of follow-up.
Results. Forthy patients were assigned to laparoscopic lymphadenectomy and 40 patients to abdominal lymphadenectomy. The laparoscopic approach was associated with a longer operative time (234.1 min vs 137.3 min) but was less painful (VAS 5.3 vs 7.9; P<0.000) and resulted in a shorter hospital stay (4.4±1 vs 7.9±1.2 days; P<0.000). At 6 weeks the quality of life was better in patients who had laparoscopic lymphadenectomy (SF-12).
Conclusion. Laparoscopic lymphadenectomy was associated with a significantly lower rate of major and minor postoperative complications and a better short term quality of life.