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Minerva Ginecologica 2006 February;58(1):55-67

language: Italian

Polycystic ovary syndrome: from physiopathology to therapy

Vicino M., Loizzi V., Scardigno D., Selvaggi L.

Dipartimento di Scienze Chirurgiche Generali e Specialistiche, Sezione di Ginecologia e Ostetricia, Università degli Studi di Bari, Bari, Italia


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Polycystic ovary syndrome (PCOS) is still a complex and heterogeneous disorder that presents a challenge for clinical investigators. It is the most common endocrine and metabolic disorder of reproductive-aged women that presents with varied symptoms such as hyperinsulinemia, anovulatory dysfunction, hirsutism, obesity and elevated incidence of cardiac problems. For these reasons, this syndrome is considered by some physicians as an endocrine and for others as a metabolic syndrome. This article will focus on the disorder of the PCOS. It will be based on an understanding of the physiopathology in order to present therapeutic recommendations.

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