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A Journal on Obstetrics and Gynecology

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Minerva Ginecologica 2002 April;54(2):145-50

language: Italian

Hormone therapies in pregnancy

Tommaselli G. A., Pellicano M., Guida M., Palomba S., Savarese F., Nola B., Ferrara C., Lapadula C., Nappi C.


Maternal endocrine disorders can have detrimental effects on the fetus and the pregnancy can affect the course of a pre-exisiting endocrinopathy or induce the onset of one of these disorders. Therapies for endocrine disorders are not always safe to administer during pregnancy. Before administering any therapy to the mother, the effects on the fetus, the degree of placental trespassing as well as the potential damaging effects must be assessed. An accurate evaluation of the risks/benefits of any drug to be used on the mother is needed, assessing above all a potential theratogenic effect. In this review, the incidence of the main endocrine disorders, their evolution during pregnancy, their effects on mothers and fetuses and new acquisition on the treatment during pregnancy are discussed.

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