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Minerva Ginecologica 2000 June;52(6):253-8

language: Italian

Hydatidiform mole with coexistent fetus. Cyto-genetic appearences, diagnosis and management

Pollio F., Daniele F., Micalef R., Citarella F., Desantis B., Ercolano S., Scaramellino M., Catalano D.


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Hydatidiform mole with coexistent fetus is an unusual entity caused by two distinct types of pregnancy: the first one is a partial hydatidiform mole, while the second is a twin pregnancy in which a mole coexists with a normal fetus. In these two separate genetic entities, the counseling and the mother-fetus prognosis are different. Two cases of mole with coexistent fetus are reported: a partial hydatidiform mole tipically tripliod and a partial mole with unusual diploid karyotype. Prenatal diagnosis is remarkable for the evaluation of fetus development related with his karyotype. Triplody excludes all hope of a nonmalformed surviving child and termination of pregnancy is desirable, while normal karyotype the possibilty of a continuation of pregnancy may be considered.

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