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A Journal on Obstetrics and Gynecology
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index
Minerva Ginecologica 2000 June;52(6):253-8
Hydatidiform mole with coexistent fetus. Cyto-genetic appearences, diagnosis and management
Pollio F., Daniele F., Micalef R., Citarella F., Desantis B., Ercolano S., Scaramellino M., Catalano D.
Hydatidiform mole with coexistent fetus is an unusual entity caused by two distinct types of pregnancy: the first one is a partial hydatidiform mole, while the second is a twin pregnancy in which a mole coexists with a normal fetus. In these two separate genetic entities, the counseling and the mother-fetus prognosis are different. Two cases of mole with coexistent fetus are reported: a partial hydatidiform mole tipically tripliod and a partial mole with unusual diploid karyotype. Prenatal diagnosis is remarkable for the evaluation of fetus development related with his karyotype. Triplody excludes all hope of a nonmalformed surviving child and termination of pregnancy is desirable, while normal karyotype the possibilty of a continuation of pregnancy may be considered.