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A Journal on Endocrine System Diseases

Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,118

Frequency: Quarterly

ISSN 0391-1977

Online ISSN 1827-1634


Minerva Endocrinologica 2013 June;38(2):181-5


Diet and physical activity “defeated” Tuberil® in treatment of childhood obesity

Ferrara P. 1, Del Bufalo F. 2, Ianniello F. 1, Franceschini A. 3, Paolini Paoletti F. 4, Massart F. 5, Saggese G. 5

1 Department of Pediatric Sciences, A. Gemelli University Hospital, Rome, Italy;
2 Campus Bio-Medico University, Rome, Italy;
3 Department of Pediatrics, Perugia University Perugia, Italy;
4 Pediatrician of the National Health System Gualdo Tadino, Perugia, Italy;
5 Department of Pediatrics, Pisa University Hospital, Pisa, Italy

Aim: Childhood obesity is remarkably spreading worldwide, involving both industrialized and low-income countries. Its prevalence, outcome and socioeconomic impact call for the attention of medical community. We conducted a monocentric, open, two-arm, parallel-group study to evaluate the efficacy at reducing appetite and increasing dietary compliance of obese children of Tuberil®, a weight-loss supplement derived from potato and devoid of side effects.
Methods: We recruited participants, children with BMI ≥85th, through direct referrals in pediatrician’s surgeries. Children were randomized to receive Tuberil® (group A) or nothing (group B), following a chronological order (A-B-A-B). Every child received a nutritionally balanced diet and had to record their appetite and to describe their meals in a diary.
Results: Even if we found a significant reduction in BMI, weight and waist circumference in both groups, no statistically significant differences between groups were noted. We did not found any significant differences in appetite between group A and B.
Conclusion: Our data show that Tuberil® has no efficacy neither in reducing appetite in children nor in increasing dietary compliance. We believe that only a nutritionally balanced diet and our attention in verifying their compliance led to the reduction in BMI, weight and waist circumferences noted in our series.

language: English


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