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A Journal on Endocrine System Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,118
Minerva Endocrinologica 2008 March;33(1):15-25
language: English, Italian
Thyroid nodular disease: an emerging problem
De Martino E., Pirola I., Gandossi E., Delbarba A., Cappelli C.
Dipartimento di Scienze Mediche e Chirurgiche, II Divisione di Medicina Interna ed Endocrinologia
Università degli Studi di Brescia, “Spedali Civili” Brescia, Italia
As a consequence of increasing application of ultrasound technology, the detection of asymptomatic thyroid nodules has generally increased. In fact, ultrasound epidemiological studies report that two third of subjects have at least a thyroid nodule, instead of 4-7% detected by clinicians. These evidences suggest the need of a rational approach to the thyroid nodule “epidemia”. The question of whether clinically unapparent thyroid lesions should be assessed by cytology is still unresolved and, moreover, the clinical significance of nonpalpable (diameter <10 mm) thyroid carcinoma is still a matter of discussion. Aim of this work is to delineate a rational approach to thyroid nodules, taking in account literature data, the most recent guidelines and our clinical experience.