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A Journal on Endocrine System Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,118
NEW DIAGNOSTIC AND THERAPEUTIC STRATEGIES: SOMATOSTATIN ANALOGS. Part II
Minerva Endocrinologica 2001 December;26(4):293-6
Efiicacy of somatostatin analogs in the treatment of neuroendocrine tumours and paraneoplastic syndromes
Sperlongano P., De Falco M., Pisaniello D., Parmeggiani D., Parmeggiani U.
Background. The authors report their experience with octreotide LAR in the adjuvant treatment of 10 patients suffering from neuroendocrine tumours and paraneoplastic syndromes.
Methods. All patients were studied preoperatively using traditional radiology and scintigraphy using octreoscan.
Results. Octreoscan was positive in all cases for somatostatin receptors. All patients with neuroendocrine tumours underwent surgery of the primary neoplasm; treatment with somatostatin was commenced at a later stage.
Conclusions. The authors' experience with octreotide LAR proved to be an efficacious means of controlling symptoms and stabilising disease without collateral effects. They conclude by affirming that octreotide LAR represents a valid therapeutic choice in the symptomatic treatment of neuroendocrine tumours.