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A Journal on Endocrine System Diseases

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Minerva Endocrinologica 1999 June;24(2):77-82

language: English

Physiopathology of the renin-angiotensin system in the ovary

De Nuccio I., Salvati G., Genovesi G., Paolini P., Marcellini L., Schiavello V., Re M.


The present review confirms the existence of the so called ''ovarian -derived prorenin-angiotensin cascade''. It ialso describes the physiopathology of the system and,cosequently,its role in the genesis of phenomena concerning reproductive function such as ovulation,steroid synthesis and folliculogenesis. Moreover,the ''ovarian-derived prorenin-angiotensin cascade'' appears to play an important role in the aethipotogenesis of diseases such as ovarian tumours,ovarian hyperstimulation syndrome and ectopic pregnancy.

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