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A Journal on Surgery

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Minerva Chirurgica 2016 June;71(3):168-72

language: English

Clinical significance of joint detection of mALB and NAG for early kidney damage in burn patients

Ji C. DING 1, Zhong L. WANG 2, 3

1 Department of Plastic Surgery at the Xuzhou Central Hospital, Xuzhou, China; 2 Graduate School, Nanjing University of Chinese Medicine, Nanjing, China; 3 The TCM Hospital of Xuzhou, Xuzhou, China


BACKGROUND: The aim of this study was to study the clinical significance of joint detection of mALB and NAG in early kidney damage in burn patients.
METHODS: Forty-five burn patients of different degrees were selected and divided into mild, moderate, severe, and heavy burns, and normal healthy controls according to their severity. Their b2- macroglobulin (b2-MG), a1-macroglobulin (a1-MG), mALB and N-acetyl-b-D-NAG were tested for 3 days, 1 week, 2 weeks, 4 weeks after the burn, respectively.
RESULTS: The urine concentration change b2-MG, a1-MG, MALB, and NAG are related to the area, depth and degree of the burn. The more serious the burn is, the higher the levels of mALB and NAG (P<0.001 or P<0.01) is.
CONCLUSIONS: Early detection of mALB and NAG is helpful for early kidney damage diagnosis in burn patients to prevent further complications.

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