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Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 0,877
Online ISSN 1827-1626
Liang W. T. 1, Wu J. M. 2, Wang F. 2, Hu Z. W. 2, Wang Z. G. 1, 2
1 Department of Thoracic Cardiovascular Surgery, Xuanwu Hospital, Capital Medical University, Xicheng District, Beijing, PR China;
2 Center for GERD, the Second Artillery General Hospital of Chinese People’s Liberation Army, Xicheng District, Beijing, PR China
AIM: The aim of the present study was to prospectively evaluate the Stretta radiofrequency (RF) treatment for gastroesophageal reflux disease (GERD) -related respiratory symptoms over a 5-years follow-up period.
METHODS: A total of 132 patients underwent the Stretta procedure between April 2007 and February 2009; 122 of the patients (92.4%) completed the 5-year follow-up. Symptom scores and PPI usage were evaluated at baseline, 6 months, 1 year, 3 years and 5 years after treatment.
RESULTS: A total of 122 patients (age, 51.7±13.0 years, M:F, 52: 70) were followed up for 5 years and their outcomes were analyzed. At 5 years after treatment, the symptom scores were significantly reduced (heartburn score, from 5.67±1.52 to 2.41±1.13; regurgitation score, from 5.43±1.66 to 2.27±1.33; chest pain score, from 4.45±1.47 to 2.40±0.88; cough score, from 6.62±1.73 to 3.14±1.43; and asthma score, from 6.83±1.46 to 3.26±1.53, P<0.001). Moreover, 56.6% of the patients were completely off PPIs.
CONCLUSION: Stretta RF significantly improves the symptoms and reduces PPI usage at 5 years. Therefore, it is a viable, effective, and minimally invasive endoluminal procedure for patients with GERD-related respiratory symptoms.