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Minerva Chirurgica 2009 February;64(1):23-35

language: English

Heart transplantation

Yun J. J., Gonzalez-Stawinski G.

Department of Cardiothoracic Surgery Cleveland Clinic Foundation, Cleveland, OH, USA


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Over the past 40 years, heart transplantation has become a routine treatment for end-stage heart failure. Over 3000 heart transplants are performed annually. Despite improvements in short-term outcomes, long-term survival remains limited. Current efforts remain directed at alleviating the shortage of donor organs, developing effective treatments for chronic rejection, and improving mechanical circulatory support for heart failure.

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