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A Journal on Surgery

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Minerva Chirurgica 2008 February;63(1):45-60

language: Italian

Hepatic resections for hepatocarcinoma in the XXI century

Ramacciato G., Mercantini P., Nigri G., Giaccaglia V., Dente M., Del Gaudio M., Lauro A., Ercolani G., Pinna A. D.

UOC Chirurgia Epatobiliopancreatica Ospedale S. Andrea Facoltà di Medicina e Chirurgia Università degli Studi di Roma La Sapienza II, Roma


Hepatic resection is today the treatment of choice for cirrhotic patients affected by hepatocellular carcinoma (HCC). Short term results are now definitely satisfactory, with a mortality rate in the referral centers lower than 5%. However, long term results are affected by a high recurrence rate, between 50% and 100%, due to the underlying cirrhosis. Notwithstan-ding the high recurrence rate, the hepatic resection guarantees a five years survival between 40% and 60%, comparable to the one offered by liver transplantation. The aim of this paper is to review the results of studies on resected cirrhotic patients affected by HCC.

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